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KMID : 0616619970030010249
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Journal of Soonchunhyang Medical College
1997 Volume.3 No. 1 p.249 ~ p.255
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Existence of Antisperm Antibody and Decrease of Sperm Motility in Patients with Chronic Prostatitis
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Abstract
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Chronic prostatitis may be related to the decrease of semen quality affecting fertility due to the existence of antisperm antibody. So we evaluated the characteristics of antisperm antibody in the control group and patients with chronic prostatitis. Statistical significance was noted in average path velocity(VAP), straight line velocity(VSL), curvilinear velocity(VCL), beat frequency(BCF), elongation of sperm motility parameters between the control group and patients with chronic prostatitis. Detection of antisperm antobody with direct and indirect immunobead test were 0%(0/11), 9.1%(1/11) in the control group and 6.3%(1/16), 37.5%(6/16) in the patients with chronic prostatitis. Titers of antisperm antibodies according to isotype (% binding, control group/ patients with chronic prostatitis) were 0/0.63±2.5(IgG), 0/0(IgA), 0.13±0.5/0(IgM) with direct immunobead test and 0.18±0.60/1.19±1.80(IgG), 0/0.06±0.25(IgG), 0/1.25±2.32(IgM) with indirect immunobead test. Statistical significance was noted in VAP, VCL, BCF between chronic prostatitis patients with and without antisperm antibody. The correlation between IgG and VAP, IgG and VCL existed. In conclusion, decreased sperm motility and the antispermantibody were found in chronic prostatitis. The antisperm antibody showed sharp contrast between the control group and the patients by indirect immunobead test, rather than by direct immunobead test. The existence of antisperm antibody correlated with sperm motility in chronic prostatitis.
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KEYWORD
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